The science of Metabolomics
The cell is the functional and morphological unit of life. There are over 75 trillion cells in our body and each of them performs thousands of biochemical functions. Any blockage of these biochemical reactions will move the body away from the healthy condition and will bring it closer to the appearance of a disease. Metabolomics studies through an advanced analysis the products of chemical reactions that occur in the body and are called metabolites. The metabolites are small molecules with a very important role in biological systems (organism) and help us understand many diseases. According to the Harvard Medical School, the measurement of metabolites is currently the simplest and most effective way to evaluate our health. Good health is the greatest wealth. Once we have robust health we will not only feel good, we will feel complete, perhaps, for the first time in our lives.
Α) Why is metabolomics useful
With the metabolomics analysis, chemical imbalances and underlying pathologies can be identified by pinpointing not only what is already happening in the organism but also stages before the disease associated with risk factors for the onset of an illness. Metabolomics is applicable to a variety of problems such as:
• Gastrointestinal disorders
• Dermatological problems
• Development Disorders
• Chronic Fatigue Syndrome
• Respiratory problems
• Chronic infections
• Hormonal disorders
• Decreased Libido
• Sleep disorders
• Athletic injuries
Metabolomics is an evaluation and preventive tool even for newborns.
B) How is the Metabolomic Profile performed?
The Metabolomic Profile is a test performed on a blood and urine sample which is carried out in one of the five leading laboratories of its kind in the US and Europe. The presence or absence of specific metabolites in a cell provides us with information about the physiology and function of biological systems. The collection of biological material (blood, urine) allows us to get critical information to optimize health status. Organic liquids reflect the health of an individual.
The metabolites analysis relies on specialized laboratory techniques such as HPLC, GC, MS-spectometry, NMR.
Metabolomics analysis is a highly regulated process in four phases:
I) Extraction (Extraction)
II) Separation and Detection (Separation and Detection)
III) Bioinformatics (Bioinformatics)
IV) Biomarker identification and data interpretation: Bio-knowledge